Bioinformatics

Suicide Epidemic: Since NIH-funded Clowns Do Not Want to Discuss It, We Will

A large number of NIH-funded parasites waste taxpayers’ money with the excuse that they are working toward improving the health of Americans. Francis Collins, the head of NIH, uses every opportunity to tell everyone how research funded by NIH helps in improving the life expectancy of Americans (a flat out lie). Yet, when research by Deaton and Case uncovered that the life expectancy of Americans of prime age (45-54) was falling, primarily due to rising suicides, Collins and his minions went completely silent.

Population Genetics of Ancient Jewish Population in India

‘Ancient’ Bene Israel Jews and late-arrived Baghdadi Jews in India started the Bollywood movie industry. Many famous early Indian actresses also came from these communities. This is not common knowledge in India, because those actresses took Muslim (Firoza Begum) or Hindu (Sulochana, Pramila) screen names.

Transistors, Translation and tRNAs

Prior to 1960s, most computers were analog computers.

Was Google Really Censoring Elhaik's Khazar Research in 2013?

In 2013, Dr. Elhaik complained about his home page at John Hopkins University mysteriously disappearing from google searches right after his first Jewish genomics paper started to gain attention. We reproduced his complaint here, and then his page came back on top again after a few days.

Organoids and the Coming Medical Revolution - (ii)

Previous segment - Organoids and the Coming Medical Revolution (i)

Transfer RNAs and Neurodegenerative Disorders

Among all biomolecules within the cell, tRNAs got the least respect. Their supposed importance ended right after the ‘adaptors’ related to entries in the genetic code table were identified (mid-60s). Since then, the attention shifted to more complex RNAs like the rRNAs.

Organoids and the Coming Medical Revolution - (i)

Among various biotechnology inventions of the last few years with potential to revolutionize medicine, nothing excites us more than growing of three- dimensional human organoids on matrigel. Therefore, we plan to devote a number of posts on this topic to keep our readers aware of the practices, potentials and challenges.

The Wall Will be Built and Mexico Will Pay for It

…to stop Americans from flooding their effective and way cheaper healthcare system.

Jewish Genetics - Forward Magazine Makes Elhaik's Work Go Viral

A few weeks back, we wrote about Dr. Eran Elhaik’s new and interesting work on tracing the roots of Ashkenazi Jews in Northeastern Turkey.

Epigenetics Debacle - Do You Feel Sad for Sid Mukherjee?

Over the weekend, Pulitzer Prize winning writer Sid Mukherjee published an article ‘Same but Different - How epigenetics can blur the line between nature and nurture’ in the New Yorker magazine.

Job Opening - Postdoctoral Scholar: Forest Genomics Database and Software Developer

(From one of our readers)

A Graph Extension of the Positional Burrows-Wheeler Transform and its Applications

from biorxiv

Freedom of Speech

Geopolitics - Several New Developments Will Define the World in the Coming Decades

One year back at this time, all of Obama’s proxy war bets were going well. Ukraine’s rebel block was in bad shape, Russian economy was in free fall, Eurozone was booming, ISIS was ready to strike at the heart of Damascus and Saudis confidently marched into Yemen expecting to control the place within a month. Even the Greeks were excited with the election of Varoufakis as finance minister.

After Docker

:)

Peak Sequencing and 'Moore's Law' Deception

Our earlier article on Illumina’s surprise announcement received a number of informative comments. We like to discuss them here, but first it is important to explain the term ‘peak sequencing’ properly. That explanation requires us to discuss the relevance of using Moore’s law for sequencing.

Someone Asked Francis Collins about the Retraction Boom. Here is What he Did not Say.

The utterly dishonest NIH head Francis Collins participated in a reddit AMA three days back. One reader asked -

The Lab That Invented Nanopore Sequencing

Yesterday, I attended an interesting talk by Ian Derrington, who is currently working as a post-doctoral researcher in the lab of professor Jens Gundlach at the University of Washington (UW). For those who do not know, Gundlach lab is the first to identify and use MspA as an efficient pore molecule for nanopore sequencing, and they published several key papers related to development of the technology over the years. In my understanding, Illumina’s licensing of MspA-related patents from UW is the basis of their IP lawsuit against Oxford Nanopore.

Comments on Our New Paper - "Sequence Analysis and Comparative Study of the Protein Subunits of Archaeal RNase P"

How did life originate on earth? What chemical properties of living objects make them different from the non-living objects? Where did the genome come from in the first place? How was life before the emergence of the genetic code? Why does the genetic code have that specific form? What biochemical advantages do the proteins get by having methionine as their first amino acid? How did the metabolic pathway evolve to its current form? How did bacteria, archaea and eukaryotes evolve into distinct kingdoms? How did multi- cellularity evolve? How did our ability to hear and smell evolve? Where did the adaptive immune system come from?

Experts Puzzled about Massive Increase in Suicide among Americans. Here is What our Non-expert Thinks

NY Times reports that the suicide rate in USA is rising very fast.